Lipid Nanoparticles Development
The Murthy laboratory has multiple projects focused on developing next generation LNPs. These projects focus on the development of LNPs that are non-immunogenic and have lower toxicity than traditional LNPs. In addition, we are also developing LNPs that disrupt endosomes efficiently and transfect non-liver organs.
Protein/Oligo Development
The Murthy laboratory has had a long-standing interest in developing protein and oligonucleotide delivery vectors. Current projects focus on using self-immolative linkers to conjugate delivery vectors to proteins and oligos.