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You are here: Home / news / Brain Delivery of CRISPR-Gold Published in Nature Biomedical Engineering!

June 29, 2018

Brain Delivery of CRISPR-Gold Published in Nature Biomedical Engineering!

The Murthy Lab, along with collaborators in Hye Young Lee’s lab at the University of Texas, San Antonio, has published the paper “Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours” in Nature Biomedical Engineering. In the paper, we demonstrate that our previously developed CRISPR-Gold gene editing delivery system may be effectively delivered into brain cells of mice via intracranial injection, and subsequently rescue mice from fragile X syndrome, a genetic autism spectrum disorder.

This paper has received significant news coverage. A selection of news articles about this paper can be found below:

The Telegraph: Autism traits could be ‘edited’ out genetic trial suggests

Science Daily: CRISPR editing reduces repetitive behavior in mice with a form of autism

Newsweek: THE END OF AUTISM? CRISPR CAN EDIT OUT AUTISM TRAITS, SCIENTISTS SAY

Popular Science: CRISPR could use gold nanoparticles to edit your brain

The Daily Californian: Study finds CRISPR-Cas9 technology can lessen autism symptoms in mice

SFGate: Study: CRISPR gene editing tech reduced autism symptoms in mice

 

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